Lenalidomide CAS NO.191732-72-6
| Name | Lenalidomide | ||
| CAS NO. | 191732-72-6 | ||
| Molecular Formula | C13H13N3O3 | Molecular Weight | 259.26 |
| MDL No. | N.A. | EINECS | 691-297-1 |
| M.P. | 265-268 °C | B.P. | 614.0±55.0 °C(Predicted) |
| Density | 1.460±0.06 g/cm3(Predicted) | Refractive Index | N.A. |
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F.P. |
N.A. | Storage condition | 2-8°C |
| Appearance | White powder | ||
| Purity | |||
| Application | Lenalidomide is an immunomodulatory drug with multiple mechanisms of action. In vitro studies have shown that lenalidomide has three main effects: 1) direct anti-tumor activity, 2) inhibition of angiogenesis, and 3) immunomodulation. In vivo, lenalidomide induces tumor cell apoptosis directly or indirectly through the suppression of bone marrow stromal cell support, anti-angiogenic and anti-osteoclast effects, and immunomodulatory activity. At the molecular level, lenalidomide has been shown to interact with the ubiquitin E3 ligase and target it to degrade the Ikaros transcription factors IKZF1 and IKZF3. | ||
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Supply Ability |
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