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Industry dynamics

  • (R)-tert-Butyl 1-(benzylamino)-3-methoxy-1-oxopropan-2-ylcarbamate

    (R)-tert-Butyl 1-(benzylamino)-3-methoxy-1-oxopropan-2-ylcarbamate

    Name: (R)-tert-Butyl 1-(benzylamino)-3-methoxy-1-oxopropan-2-ylcarbamate Synonyms: Lacosamide intermediate; BOC-serine methyl ether benzylamine; tert-butyl N-[(1R)-1-(benzylcarbamoyl)-2-methoxyethyl]carbamate CAS No.: 880468-89-3 EINECS No.: 1592732-453-0 Chemical Formula: C₁₆H₂₄N₂O₄ Molecular We...
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  • (tert-Butoxycarbonyl)-D-serine; Boc-D-Ser

    (tert-Butoxycarbonyl)-D-serine; Boc-D-Ser

    Name: Boc-D-Serine Names: (tert-Butoxycarbonyl)-D-serine; Boc-D-Ser; N-BOC-D-SERINE; N-(tert-Butoxycarbonyl)-D-serine; N-[(1,1-Dimethylethoxy)carbonyl]-D-serine; BOC-D-SERINE H2O CAS No.: 6368-20-3 EINECS No.: 444-670-6 (EC No.: 613-313-8) Chemical Formula: C₈H₁₅NO₅ Molecular Weight: 205.21 InChI...
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  • Methyl Trifluoromethanesulfonate (CAS 333-27-7): How Highly Reactive Methylating Agents Drive a Leap in Innovative Drug Synthesis Efficiency

    Methyl Trifluoromethanesulfonate (CAS 333-27-7): How Highly Reactive Methylating Agents Drive a Leap in Innovative Drug Synthesis Efficiency

    In today’s increasingly compressed innovative drug development cycle, the precise introduction of a methyl group often determines the druggability and patent potential of candidate compounds. Methyl trifluoromethanesulfonate (Methyl Triflate or MeOTf, CAS: 333-27-7), as one of the most reac...
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  • Why does the choice of methylating agent determine the success or failure of a synthetic route?

    Why does the choice of methylating agent determine the success or failure of a synthetic route?

    I. Why does the choice of methylating agent determine the success or failure of a synthetic route? In innovative drug development and the synthesis of high-end fine chemicals, methylation is one of the most frequent transformations. Statistics show that over 67% of FDA-approved small molecule dru...
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  • 4,6-Dihydroxypyridazine-3-carboxylic acid

    4,6-Dihydroxypyridazine-3-carboxylic acid

    Other Names: 4-Hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid; 4-hydroxy-6-oxo-1H-pyridazine-3-carboxylic acid; Deucravacitinib Impurity 9; BMS-986165 Related Compound 4; EOS-61508; 3-Pyridazinecarboxylic acid, 1,6-dihydro-4-hydroxy-6-oxo- CAS Number 1442437-21-9 (Main); 1823277-97-9 (Back...
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  • 4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide/4,6-Dichloro-N-methylpyridazine-3-carboxamide-d3

    4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide/4,6-Dichloro-N-methylpyridazine-3-carboxamide-d3

    Name:4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide/4,6-Dichloro-N-methylpyridazine-3-carboxamide-d3  Synonyms: BMS-986165 Related Compound 5; Deucravacitinib Impurity 10; 4,6-dichloro-N-(trideuteriomethyl)pyridazine-3-carboxamide; 4,6-dichloro-N-trideuteromethylpyridazine-3-carboxamide; 4,6-...
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  • Deucravacitinib / Methan-d3-amine hydrochloride

    Deucravacitinib / Methan-d3-amine hydrochloride

    Name: Deucravacitinib / Methan-d3-amine hydrochloride   English Other Names: Methyl-d3-ammonium chloride; (2H3)methylammonium chloride; Monomethyl-d3-ammonium chloride; Methyl-d3-amine monohydrochloride; Deuterated methylamine hydrochloride; METHYL-D3-AMINE HCl; D3-Methyl-amine HCl; EOS-61951; tr...
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  • Diethylaminosulfur trifluoride

    Diethylaminosulfur trifluoride

    Name: Diethylaminosulfur trifluoride Other Names: DAST; (Diethylamino)sulfur trifluoride; (Diethylamino)sulphur trifluoride; ET2NSF3; Sulfur trifluoride diethylamine complex CAS No.: 38078-09-0 EINECS No.: 253-771-2 Chemical Formula: C₄H₁₀F₃NS Molecular Weight: 161.19 InChI 1S/C₄H₁₀F₃NS/c1-3-8(4-...
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  • 1,3-Bis-(2,4,6-trimethylphenyl)-2-(imidazolidinylidene)(dichlorophenyl-methylene)(tricyclohexylphosphine)ruthenium (II)

    Name 1,3-Bis(2,4,6-trimethylphenyl)-2-(imidazolidinylidene)(dichlorobenzylidene)(tricyclohexylphosphine)ruthenium(II) Synonyms Grubbs 2nd Generation Catalyst; Grubbs Second Generation Catalyst; Grubbs Catalyst; Benzylidene-1,3-bis(2,4,6-trimethylphenyl)-2-(imidazolin-2-ylidene)(tricyclohexylphosp...
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  • [1,3-bis(diphenylphosphino)propane]palladium(II)

    [1,3-bis(diphenylphosphino)propane]palladium(II)

    Name: Dichloro[1,3-bis(diphenylphosphino)propane]palladium(II) Other Names: [1,3-bis(diphenylphosphino)propane]palladium(II) chloride, 1,3-bisdiphenylphosphinopropane dichloride, [1,3-bisdiphenylphosphino]palladium chloride, bis(1,3-diphenylphosphino)propyl dichloride (II) English Other Names: (1...
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  • 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene

    4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene

    Name: 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene Other Names: Xantphos; 9,9-dimethyl-4,5-bisdiphenylphosphinoxanthene; 4,5-bisdiphenylphosphino-9,9-dimethylxanthene; dimethylbisdiphenylphosphinoyloxanthene English Other Names: XANT PHOS; Dimethylbisdiphenylphosphinoxanthene; (9,9-Dimethyl-9H...
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  • 2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl

    Name: 2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl Other Names: tBuXPhos; t-Bu XPhos; tert-Butyl X-Phos; 2-Di-t-butylphosphino-2′,4′,6′-tri-i-propyl-1,1′-biphenyl; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine CAS Number: 564483-19-8 EINECS No. 639-817-8 Chemical Formula C₂...
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